Adult Mesenchymal Stem Cells for Tissue Engineering Versus Regenerative Medicine

Adult mesenchymal stem cells (MSCs) can be isolated from bone marrow or marrow aspirates and because they are culture-dish adherent,
they can be expanded in culture while maintaining their multipotency.

Dominici 2006 ISCT Minimal criteria for defining multipotent MSCs

Biologic and clinical interest in MSC has risen dramatically over the last two decades, as shown by the ever-increasing number of research teams studying these cells.  Not only are established laboratories focusing on MSC but new investigators are rapidly being attracted to the field, which will undoubtedly accelerate scientific discovery and the development of novel cellular therapies.

Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into tissues including bone, cartilage and
adipose in vitro, but it is their trophic, paracrine and immunomodulatory functions that may have the greatest therapeutic
impact in vivo.

Engineering Principles of Clinical Cell-Based Tissue Engineering

Tissue engineering is a rapidly evolving discipline that seeks to repair, replace, or regenerate specific tissues or organs by translating fundamental knowledge in physics, chemistry, and biology into practical and effective materials, devices, systems, and clinical strategies.


Autologous Platelet-Rich Plasma Mixed with Purified Fat Graft in Aesthetic Plastic Surgery

Platelet-rich plasma (PRP) is a platelet concentrate that has widely been used to accelerate the healing of soft and hard tissues. The preparation of PRP has been described by several authors. Preparation protocols vary from system to system, depending on the concentration of different integrating proteins. The objective of this article is to describe the principal use of PRP mixed with fat grafts in aesthetic plastic surgery.

Platelet-Rich Plasma to Promote Healing and Prevent Seroma Formation in Abdominoplasty Procedures

The intent of this study this study was to evaluate the use of platelet-rich concentrate on patients undergoing either full abdominoplasty or crescent tuck abdominoplasty surgery

Treatment of Large Skin Necrosis Following a Modified Avelar Abdominoplasty with the Erchonia EML 635 nm Laser and Platelet-Rich Plasma

Skin necrosis of the flap and delayed wound healing are common complications of abdominoplasty surgery. A case report is presented of a patient who was treated with the 635 nm or low-level laser therapy (LLLT) and platelet-rich plasma (PRP). Both of these modalities have been shown to accelerate wound healing and improve the appearance of the scar.

The Use of Autologous Platelet-Rich Plasma (Platelet Gel) and Autologous Platelet-Poor Plasma (Fibrin Glue) in Cosmetic Surgery

The purpose of this study was to evaluate a new technique of harvesting and preparing autologous platelet gel and autologous fibrin glue (body glue) and to evaluate their effectiveness in stopping capillary bleeding in the surgical flaps of patients undergoing cosmetic surgery.

The synergy between lasers and adipose tissues surgery in cervicofacial rejuvenation: histopathological aspects

 This is a study aiming to emphasize the histopathological changes occurred following various tissue surgeries for cervicofacial rejuvenations.

Platelet-Rich Plasma (PRP) Utilized To Promote Greater Graft Volume Retention in Autologous Fat Grafting

This study aims to investigate the effects of platelet-rich plasma (PRP) on autologous fat grafts when used in conjunction with each other in soft tissue augmentation and reconstruction.

Safety, Efficacy, and Utility of Platelet-Rich Fibrin Matrix in Facial Plastic Surgery

This study evaluates the clinical safety and efficacy of the use of autologous platelet-rich fibrin matrix (PRFM) in facial plastic surgery.


The Effect of Autologous Activated Platelet Rich Plasma (AA-PRP) Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

This pilot study suggests that PRP may serve as a safe and effective treatment option in AA and calls for more extensive controlled studies with this method

Study of Platelet Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One Year Period

To evaluate the efficacy and safety of PRP injections in the scalp of patients with androgenetic alopecia.

Treating Hair Loss With Platelet-Rich Plasma

This technique has become an effective alternative for a common cosmetic condition that has traditionally had limited treatment options.

Platelet-Rich Plasma in Androgenic Alopecia: Myth or an Effective Tool

Platelet-rich plasma (PRP) has become a newer method for the treatment of various types of alopecia. In this prospective study, safety, efficacy and feasibility of PRP injections in treating androgenic alopecia were assessed.

Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

This study  investigates the effects of PRP on hair growth using in vivo and in vitro models.

New Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach

Efficacy of platelet rich plasma in treatment of androgenic alopecia

The objective of this study was to investigate the clinical efficacy of PRP in treatment of androgenic alopecia.

A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata

To evaluate the efficacy and safety of PRP for the treatment of AA in a
randomized, double-blind, placebo- and active-controlled, half-head, parallel group study

The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

This study provides a new perspective and contribution to baldness surgery with follicular unit megasessions, and demonstrates an improvement that can be introduced into baldness surgery clinics with less morbidity and a low cost-to-benefit ratio.


Effect of platelet-rich plasma on ultraviolet b-induced skin wrinkles in nude mice

Although more in vivo studies and research about the mechanism of PRP are required, the results of this study indicate that PRP is effective in the rejuvenation of photoaged skin.

Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-Rich Plasma

The purpose of this study is to evaluate the benefits of PRP in the wound healing process after FxCR

Face and Neck Revitalization with Platelet-rich Plasma (PRP): Clinical Outcome in a Series of 23 Consecutively Treated Patients

Face and neck revitalization with PRP is a promising easy-to-perform technique in face and neck rejuvenation and scare attenuation.

Induction of Dermal Collagenesis, Angiogenesis, and Adipogenesis in Human Skin by Injection of Platelet-Rich Fibrin Matrix

This study evaluates the histological changes induced in human skin by injection of autologous plateletrich fibrin matrix (PRFM).

Platelet Rich Fibrin Matrix with Facial Collagen Genesis and Epidermal Regeneration

The purpose of this study to determine if Platelet-rich fibrin matrices can induce an improvement in facial volume and mollify epidermal age-related negative remodeling.

PRP - Red Blood Cells

Leukocyte Rich vs. Leukocyte Poor Biologics

Overview of the Components in Platelet Rich Plasma (PRP) and Their Roles in Healing

Role of White Blood Cells in Blood- and Bone Marrow-Based Autologous Therapies

The aim of this review is to address these common misconceptions which will enable better development of future orthopedic medical devices.

Le 2019 PRP Clinical Evidence Review

PRP remains a promising treatment for musculoskeletal maladies, and clinical data to date have shown that PRP is safe

LR vs. LP Education

This document provides an overview of the components in Platelet Rich Plasma (PRP) and their roles in healing

Tru Training Powerpoint

This is a Powerpoint which discusses the basic biology of platelet growth factors and how PRP fits into this space.

Device Training

Magellan - PRP





Device Training



Device Training